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Established findings within preclinical literature: GLP-1R ligands can be examined through receptor binding, cyclic AMP assays, receptor trafficking studies, and -arrestin recruitment models

It is believed that short-latency OPs (OP1 and OP2) are generated mainly by cones, while rods play a major role in the formation of longer latency OPs (OP3, OP4, and OP5) (Liu et al